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Role of 3 percent topical Moringa gel as intervention in participants having Oral leukoplakia

COMPARATIVE ASSESSMENT OF EFFECTIVENESS OF MORINGA GEL 3 PERCENT VERSUS RETINOIC ACID 0.025 PERCENT CREAM IN THE TREATMENT OF ORAL LEUKOPLAKIA- A PROSPECTIVE DOUBLE BLIND RANDOMIZED CONTROLLED STUDY - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/089305
Enrollment
50
Registered
2025-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K132- Leukoplakia and other disturbancesof oral epithelium, including tongue

Interventions

Intervention1: Topical Moringa gel 3%: thrice daily for 4 weeks, after that thrice daily every 15 days follow up for 1 month Control Intervention1: Topical RETINOIC ACID (0.025%) CREAM: thrice dai

Sponsors

Dr Siddhi Rane
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Clinically Diagnosed cases of oral leukoplakia 2)Patients above 21 years of age 3)Patients with no contraindications or documented allergies to the medications which are being used for study 4)Patients willing to give consent

Exclusion criteria

Exclusion criteria: 1)lesions showing ulceroproliferative changes 2)Previously treated patients of oral leukoplakia in last 3 months or those who have left treatment inbetween or undergoing any other treatment modality 3)Patients mentally retarded 4)Pregnant and lactating mother

Design outcomes

Primary

MeasureTime frame
Sizeof lesion(multiple sitesor bilaterally using vernier caliper) Secondary changes New lesion Timepoint: weekly for 4 weeks after that 15 days for 1 month

Secondary

MeasureTime frame
To record the adverse reactions if any with both the drugs in either of the two groups To record the recurrence of the lesion in any of the two groupsTimepoint: weekly for 4 weeks after that 15 days for 1 month

Countries

India

Contacts

Public ContactDr Siddhi Rane

Government Dental College and Hospital Mumbai

drvijayaomr@gmail.com9676557606

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026