Comparison of Intravenous Versus Nebulized Dexmedetomidine for hemodynamic stability after intubation

Comparison of Intravenous Versus Nebulized Dexmedetomidine for Attenuation of Laryngoscopy and Intubation-Induced Sympathoadrenal Stress Response-A Randomised, comparative clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089300

Enrollment

120

Registered

2025-06-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: NIL: NIL Intervention2: Effect of nebulized Dexmedetomidine for attenuation of laryngoscopy and intubation induced sympathoadrenal stress response: Patients in the intervention group r

Eligibility

Inclusion criteria

Inclusion criteria: A) Patients posted for elective surgery under general anesthesia requiring endotracheal intubation B) Age: 18- 60 years C)Gender: Either gender D)ASA I, II and III

Exclusion criteria

Exclusion criteria: Patient refusal Dexmedetomidine allergy Preoperative sore throat or upper respiratory infection Significant cardiac pulmonary or hepatorenal disease Body mass index more then thirty kg per meter swerve Predictive difficult airway Pregnant patient

Design outcomes

Primary

Measure	Time frame
Nebulized dexmedetomidine may provide a favourable alternative to intravenous route for attenuation of sympathoadrenal stress response to intubationTimepoint: Till 10 minutes after intubation	—

Secondary

Measure	Time frame
Preventing post operative sore throatTimepoint: Post operative 24 hour	—

Countries

India

Contacts

Public ContactDr Darshna patel

Government medical College BARODA

dr.darshna1968@yahoo.com9925013155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026