Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: fentanyl or dexmeditomedine as adjuvants for hyperbaric levobupivacaine: Study population is divided into 3 groups A,B and C.
Group A will receive 14mg hyperbaric levobupivacaine alon
Sponsors
Jawaharlal Nehru Institute of Medical Sciences, Imphal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 - 60 years undergoing infraumbilical surgeries 2. Patients who are categorised under ASA I and II 3. Patients who have signed a written informed consent form
Exclusion criteria
Exclusion criteria: Patients refusal 1. Pregnant women 2. Patients with spine deformities, local infection near the injection site 3. Patients with history of allergy to study drugs 4. Patients with abnormal coagulation profile
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the onset and duration of sensory and motor block of intrathecal hyperbaric levobupivacaine alone, hyperbaric levobupivacaine with fentanyl, and hyperbaric levobupivacaine with dexmedetomidineTimepoint: The level of sensory block will be assessed by pin prick method every minute after drug administration till 15 minutes from start, then every 15 minutes till the completion of surgery. Motor block will be assessed by Modified Bromage Scale every minute till Modified Bromage grade 3 is achieved. Then motor block assessed every hourly for 3 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic effects. Heart rate, blood pressure, oxygen saturationTimepoint: baseline, then every 5 minutes after administration of drug till the surgery ends;Total number of rescue analgesia requiredTimepoint: till 12 hours after completion of surgery;Analgesic profileTimepoint: 1. Visual Analog Scale at the end of surgery 2. Visual Analog Scale when patient asks for 1st rescue analgesic dose | — |
Countries
India
Contacts
Public ContactKEISHAM UPENDRA SINGH
Jawaharlal Nehru Institute of Medical Sciences, Imphal
Outcome results
None listed