Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: DEXMEDETOMIDINE: Patients in group Dex will be administered a loading dose of 0.3-1mcg/kg for 10min followed by continuous infusion of dexmedetomidine @ 0.3-0.7mcg/kg/hr till the end of
Sponsors
IMS&SUM hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients posted for elective spine surgeries with controlled hypertension 2.Age group of 20 to 65 years 3.Patients belonging to ASA class-2 4.Patients who have given informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1.Patient not giving consent 2.known allergy to either drug 3.Opioid dependence 4.Any coagulation disorders 5.Patient taking anticoagulant drugs 6.Re-operative surgery 7.Uncontrolled hypertension & diabetes 8.Patients with significant cardiovascular or respiratory diseases 9.Patients with neurological or psychiatric disorders affecting pain perception reporting
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of dexmedetomidine versus remifentanil in achieving controlled hypotension during spine surgeriesTimepoint: Baseline, 10 minutes, 30 minutes, 60 minutes, at extubation, 30 minutes after extubation, 60 minutes after extubation, 90 minutes after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate intraoperative blood loss, hemodynamic stability, Postoperative pain scores(VAS), duration of sedation and adverse effects associated with each agentTimepoint: Baseline, 10 minutes, 30 minutes, 60 minutes, at extubation, 30 minutes after extubation, 60 minutes after extubation, 90 minutes after extubation | — |
Countries
India
Contacts
Public ContactKamma Manisha chowdary
IMS&SUM hospital
Outcome results
None listed