Health Condition 1: K30- Functional dyspepsia
Conditions
Interventions
Intervention1: Vonoprazan: Tab Vonoprazan 20mg once a day for 4 weeks
Control Intervention1: Esomeprazole: Tab Esomeprazole 40 mg once a day for 4 weeks
Sponsors
IMS SUM Hospital SOA university
Eligibility
Inclusion criteria
Inclusion criteria: APatient with diagnosis of Functional dyspepsia as per ROME IV CRITERIA Age more thsn 18 years of both sex Not taken any other drugs for the Dyspepsia symptoms for last 2 weeks before the date of diagnosis
Exclusion criteria
Exclusion criteria: Patient unwilling to give consent Pregnancy, Lactating women Patient with H. pylori infection detected by Urease test Peptic ulcer disease Anxiety and Depression unrelated to Dyspepsia Patient taking Anti-psychotics Chronic lung ,liver and kidney disease Cancer Cardiac co-morbidities Active Alcoholism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of vonoprazan 20 mg and esomeprazole 40 mg which will be assessed by Global overall symptom scale(GOSS) 2.Improvement in quality-of-life evaluation by Nepean dyspepsia index 3.Mental health status using Hospital Anxiety and Depression Scale(HADS)Timepoint: 0 week, 4 weeks , 6weeks of drug administrated | — |
Secondary
| Measure | Time frame |
|---|---|
| To Assess the adverse effects of the drugsTimepoint: 4 weeks, 6 weeks of drug administration | — |
Countries
India
Contacts
Public ContactDr Snigdha Sucharita
IMS and SUM Hospital Bhubaneswar
Outcome results
None listed