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Role of galactomannan test in diagnosis of fungal pneumoniae in blood cancer patients

Evaluation of diagnostic performance of galactomannan assay and analysis of associated risk factors for fungal pneumonia among hemato-lymphoid cancers patients at a tertiary cancer center. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/089153
Enrollment
70
Registered
2025-06-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J168- Pneumonia due to other specified infectious organisms

Interventions

Intervention1: Nil: Nil

Sponsors

Homi Bhabha Cancer Hospital & Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Varanasi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pediatric or adult hematolymphoid cancer patients. 2. Among pediatric population, patient with age group of 1-14 years will be included in the study 3. Patient with febrile neutropenia despite of appropriate antibiotic treatment for more than 4 days with positive galactomannan assay with/without radiological finding suggestive of fungal pneumonia. OR Febrile neutropenic patient with clinical suspiciousness for fungal pneumonia and consistent with radiological finding towards fungal pneumonia

Exclusion criteria

Exclusion criteria: 1. Pediatric patient with age of less than or equal to 1 year 2. Patient with negative galactomannan assay and radiological imaging not suggesting fungal pneumonia.

Design outcomes

Primary

MeasureTime frame
1)Diagnostic performance of Galactomannan assay. 2)Analysis of associated risk factors for Invasive aspergillosis in adult and pediatric hemato-lymphoid cancer populationTimepoint: 1)Within 10 days of enrollment in the study 2)Within 10 days of enrollment in the study On the day of enrollment

Secondary

MeasureTime frame
1)Analysis of available diagnostic criteria (EORTC and Asp ICU) for IA among cancer population.Timepoint: 1)Within 10 days of enrollment in the study

Countries

India

Contacts

Public ContactDr Anmol Singh

MPMMCC and HBCH, Tata Memorial Centre

rahulsarode86@gmail.com9930330391

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026