A study to compare two sutures- Barbed and Non-Barbed (Simple Vicryl)Sutures and to evaluate operative time, healing of donor site and minimum scar formation in participants undergoing oral submucosa fibrosis.

Comparison of outcomes of knotless barbed sutures and non-barbed sutures used as wound closure materials for subcuticular suturing at the nasolabial donor site in patients undergoing surgical rehabilitation for oral submucous fibrosis. - Knotless barbed suture

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089139

Enrollment

Registered

2025-06-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 3-0 polyglyconate barbed suture [COVIDIENV-LOC 180] : 3-0 polyglyconate barbed suture [COVIDIENV-LOC 180] will be placed over donar site of nasolabial flap. The flap will then be sutur

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with grade III/grade IV OSF requiring surgical intervention and reconstruction with nasolabial flap.

Exclusion criteria

Exclusion criteria: Patient underwent previous facial surgery. Patients with known allergic history to the contents in the suture material. Patients who had undergone radiotherapy. Patients with other than ASA Group I.

Design outcomes

Primary

Measure	Time frame
less wound closure time and better wound healing.Timepoint: during wound closure, Wound healing- 7th pod and 15th pod.	—

Secondary

Measure	Time frame
less scar formation.Timepoint: 1st and 2nd month	—

Countries

India

Contacts

Public ContactDr Shende Himanshu Arvind

Datta Meghe Institue Of Research And Education

drnitinbhola@gmail.com9970070607

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026