Comparision ofSilver nanoparticles with Platelet Rich fibrin vs bone graft with Platelet rich fibrin by observing clinical healing and bone fill in intrabony defect of gums

Comparative Evaluation of Silver Nano Particles with PRF Vs PRF With Xenograft In Two-Walled Intra-bony Defects: A Clinico-Radiographic study - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089135

Enrollment

Registered

2025-06-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M278- Other specified diseases of jaws

Interventions

Intervention1: silver nanoparticles (20-30nm): silver nanoparticles with PRF on Two-walled intra-bony defect by Open flap debridement Control Intervention1: Xenograft: Xenograft with PRF on Two-walled

Eligibility

Inclusion criteria

Inclusion criteria: Periodontitis Within 25 to 55 Years of Age Probing Pocket Depth more than 5 Mm Evidence Of two-walled Angular defects as determined by intraoral periapical radiograph

Exclusion criteria

Exclusion criteria: Undergoing Anti coagulant therapy Systemic Conditions such as Myocardial Infarction, Stroke, Renal diseases, Carcinoma etc In the Past 6 Months Adverse Habit such as Tobacco consumption & Smokers Pregnant & Lactating Women

Design outcomes

Primary

Measure	Time frame
Radiographic Depth of Intra bony DefectTimepoint: at 6 months	—

Secondary

Measure	Time frame
Increase in Clinical Attachment Level Probing depthTimepoint: 2 weeks, 4 weeks, 3 month, 6 month	—

Countries

India

Contacts

Public ContactDr Samruddhi Sunil Thakare

SMBT IDSR, DHAMANGAON, NASHIK

seekvp@gmail.com7507712339

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026