Health Condition 1: E114- Type 2 diabetes mellitus with neurological complications
Conditions
Interventions
Intervention1: Waj: 2 Capsules of Waj (containing 500 mg powder of Acorus calamus Linn. in each capsule) two times a day.
Control Intervention1: Pregabalin: One Capsule of Pregabalin 75 mg two times
Sponsors
NATIONAL INSTITUTE OF UNANI MEDICINE
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosed cases of DPN with Type 2 DM. History of DPN with or without medication within the period of 6 months to 60 months. Subjects of DPN with Toronto clinical scoring system score more than 5 up to 11. HbA1c less than 7. All genders. Age between 30 and 60 years. Normotensive (without taking any anti-hypertensive medicines)
Exclusion criteria
Exclusion criteria: Known cases of peripheral nerve dysfunction; vitamin deficiency (B12 and E), peripheral vascular disease (peripheral artery disease, varicose vein, deep vein thrombosis, Raynaud s disease, Buerger s disease). History of positive alcoholism. Patient on Insulin. Known history of thiazolidinedione antidiabetic agents (peripheral edema with pregabalin). Patients with a history of Cancer, Autoimmune diseases (Multiple sclerosis, GB syndrome, Myasthenia gravis), and vasculitis (Polyarteritis nodusa). Pregnant & lactating mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in Visual Analogue Scale (VAS) Improvement in vibration perception threshold (VPT)Timepoint: For VAS at every 15th day (0th, 15th, 30th, 45th, and 60th). For VPT pre and post. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in TCSS. Improvement in DNS. Improvement in EuroQol 5 Dimension 5 Level (EQ 5D 5L).Timepoint: Every 15th day (0th, 15th, 30th, 45th, and 60th). | — |
Countries
India
Contacts
Public ContactDR MOHD SHAHID
NATIONAL INSTITUTE OF UNANI MEDICINE
Outcome results
None listed