Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: Platelet Rich Plasma injection: Intra-articular PRP injections
Three doses of PRP with each dose 3 ml, will be administered in the intra-articular knee one week apart.
Control Interven
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Patients with primary OA knee fulfilling ACR criteria (1986) Patients with OA knee symptoms of more than 3 months duration
Exclusion criteria
Exclusion criteria: Patients with secondary knee osteoarthritis Uncontrolled Hypertension and Diabetes Mellitus Type 2 Inflammatory arthritis, spondyloarthropathies. History of trauma with diagnosed ligament tear History of surgery, manipulation, mobilization, or arthroscopy History of steroid, local anaesthetic, or hyaluronic acid injection over the last 3 months Bleeding disorders, patients using anticoagulant or antiaggregant medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study will show improvement, if any, in serum COMP levels in OA knee patients receiving PRP injection at 6 weeks follow-up.Timepoint: baseline 0 weeks, 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| The study may also establish a correlation between change in COMP levels & the functional & pain status of the patients after PRP injections.Timepoint: baseline 0 weeks & 8 weeks | — |
Countries
India
Contacts
Public ContactDr Diganta Borah
AIIMS Guwahati
Outcome results
None listed