Health Condition 1: K639- Disease of intestine, unspecified Health Condition 2: K769- Liver disease, unspecified
Conditions
Interventions
Intervention1: Indigenous HFNC device: Preoxygenation through indigenously developed TrueOxy+ HFNC device in Group A
Control Intervention1: Standard HFNC Device: Preoxygenation through standard HFNC
Sponsors
Indian Council of Medical Research (ICMR), New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 18 to 50 years (Adult Patients) , 2. ASA PS I & II, 3. Adult patients who will undergo major abdominal surgery at the Main Operation Theatre (OT), Nehru Hospital & Extension, PGIMER, under general anaesthesia and requires arterial blood gas monitoring. 4. Patients with informed consent for participation in the study.
Exclusion criteria
Exclusion criteria: 1. Less than 18 years and Greater than 50 years. 2. ASA PS III & IV 3. History of severe respiratory, cardio-vascular, renel, known case of asthma, COPD, nasal facial trauma. 4. Patient requiring oxygen supplementation before induction of Anaesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in the PaO2 at the end of preoxygenation between the two devices, i.e., the TrueOxy+ HFNC device and the reference HFNC device (Fisher & Paykel Airvo 2 HFNC device).Timepoint: 1. 0 Minutes 2. 3 Minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| EtO2, EtCO2, RR, BP, SpO2, HR levels during preoxygenation. Timepoint: (time frame: every 30 seconds till the end of preoxygenation (total 3-minute period));Other ABG parameters like pH, PCO2, HCO3, BE/BD from the sampleTimepoint: at the end of preoxygenation;Patient Comfort assessed on an ordinal scaleTimepoint: at the end of preoxygenation. | — |
Countries
India
Contacts
Public ContactDr Shiv Lal Soni
Postgraduate Institute of Medical Education and research, Chandigarh ( INDIA)
Outcome results
None listed