Health Condition 1: F311- Bipolar disorder, current episodemanic without psychotic features
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
AIIMS NEW DELHI
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for cases 18 to 45 years and Meeting DSM 5 criteria for Bipolar 1 disorder current episode mania. Inclusion criteria for Controls comprise 18 to 45 years, and screen negative using PHQ-9 and GAD-
Exclusion criteria
Exclusion criteria: Exclusion criteria for Cases: 1. Any co occurring psychiatric illness or intellectual disability( as per known history) 2. Any current use of substance apart from nicotine ( as per known history) 3. Any known medical condition that has the potential to interfere with the the study assessments 4. Pregnancy or lactation 5. ECT in past 1 month Exclusion criteria for Controls: 1. GAD score>10 or PHQ-9 score>10 2. Any psychiatric illness or intellectual disability( as per known history) 3. Any current use of substance apart from nicotine ( as per known history) 4. Any known medical condition that has the potential to interfere with the the study assessments 5. Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Assess and compare the serum uric acid across manic patients and matched healthy controls 2)Assess the clinical profile, including symptom severity and its association with serum uric acid in patients with mania at baseline and prospective follow-upTimepoint: Baseline, followed by 3 time points in next 10 weeks , that is week 2,4, and 10. Completers will be any 2 time points including baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the clinical profile, including symptom severity and its association with serum uric acid in patients with mania at baseline and prospective follow-upTimepoint: Baseline, followed by 3 time points in next 10 weeks , that is week 2,4, and 10. Completers will be any 2 time points including baseline | — |
Countries
India
Contacts
Public ContactDr Raman Deep
AIIMS, New Delhi
Outcome results
None listed