Recovery Quality After Gallbladder Surgery: The Role of Intraperitoneal Local Anesthetic and Dexamethasone

Evaluation of the Quality of Recovery Following Intraperitoneal Local Anesthetic instillation with or without Dexamethasone in Patients Undergoing Laparoscopic Cholecystectomy under General Anaesthesia: A double blind Randomized controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/06/089058

Enrollment

100

Registered

2025-06-18

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K819- Cholecystitis, unspecified

Interventions

Intervention1: 30 ml of 0.25 % bupivacaine plus 8 mg. Dexamethasone: A single dose of 30 ml of 0.25 % bupivacaine plus 8 mg. Dexamethasone will be administered through intraperitoneal route before rem

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients 18 - 70 yrs of age, with American Society of Anesthesiologists (ASA) physical status Iâ??II scheduled for elective laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Patients allergic to study drugs,Patients on steroid therapy,Patients with mental health issues

Design outcomes

Primary

Measure	Time frame
Quality of recovery (QoR) following intraperitoneal instillation of bupivacaine with or without Dexamethasone in patients undergoing laparoscopic cholecystectomy, using the QoR-15 (QoR-15) questionnaireTimepoint: Baseline QoR-15 score- 12 hours prior to Surgery Final QoR-15 score - 24 hours after surgery	—

Secondary

Measure	Time frame
1.Time to first rescue analgesia. 2.Total amount of rescue analgesia in the first 24 hrs postoperatively. 3.Incidence of nausea and vomiting during the first 24hrs, postoperatively. 4.Time to discharge after surgery Timepoint: 24 hours after surgery and at the time of discharge	—

Countries

India

Contacts

Public ContactRISHABH JAJU

All India institute of Medical Sciences,Deoghar

rishabh.anesthesiology@aiimsdeoghar.edu.in07742454477

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026