Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Dr Tarun Tomar
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with breast cancer and receiving Anthracycline and cyclophosphamide-based highly emetogenic chemotherapy Adequate Organ function -serum creatinine less than 2.0 mg/dL; serum bilirubin less than 2.0 mg/dL; serum glutamic-oxaloacetic transaminase or serum glutamic-pyruvic transaminase less than or equal to three or more times the upper limits of normal; absolute neutrophil count greater than 1,500 mm3b)
Exclusion criteria
Exclusion criteria: Patients with nausea in the 24 hours before beginning chemotherapy; Concurrent radiation therapy; Patients suffering from tumors with brain metastasis/ or with serious psychiatric conditions; Acutely ill patients such with serious liver and renal disorders and serious cardiac disorders with left ventricular ejection fraction less than 50%; Pregnant and lactating women; Unable or refused to cooperate in the evaluation form of nausea and vomiting.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rating of nausea and vomiting will be by using MAT tool and CTCAE version 5.0 The proportion of patients achieving Overall complete response, Complete response during acute phase, Complete response during delayed phase, Overall complete protection, and No nauseaTimepoint: At baseline and 2 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| not applicableTimepoint: not applicable | — |
Countries
India
Contacts
Public ContactDr Tarun Tomar
Kasturba Medical College and Hospital
Outcome results
None listed