Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Reversal agent for comparison: Group 1/ N: Neostigmine (2.5mg)-glyco (0.4mg) for reversal i.v.
Group 2/ S: Sugammadex 2mg/kg iv for reve
Sponsors
Ruby Hall Clinic
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA 1/2 cases 2. BMI-18-26 3.No contraindication for receiving rocuronium 4.Laparoscopic surgeries lasting upto 2-3 hrs
Exclusion criteria
Exclusion criteria: 1.Allergy to rocuronium, sugammadex or neostigmine 2.malignant hyperthermia 3.hepatic or renal insufficiency 4.neuromuscular diseases 5.inability to give consent 6.Head, neck-face surgeries, thoracic and open abdominal surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the post operative residual paralysis in both groups using TOF, clinical assessment and ultrasound Timepoint: 3 readings of TOF pre extubation 3 readings of TOF post extubation at 15, 30 and 45 minutes Clinical assessment at same time points respiratory muscle assessment by sonography at 30 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events in either group Group 1/ N: Neostigmine (2.5mg)-glyco (0.4mg) for reversal Group 2/ S: Sugammadex 2mg/kg iv for reversal Timepoint: around extubation-45 minutes after extubation when patient in recovery room | — |
Countries
India
Contacts
Public ContactBhavya A B
Ruby Hall Clinic Pune
Outcome results
None listed