Evaluation of pulpal numbness and injection pain using a common injection technique with three forms of same numbing medicine warmed up, less acidic and conventional in lower back teeth with severe tooth ache.

Evaluation of Pulpal Anesthesia And Injection Pain Using Inferior Alveolar Nerve Block With Pre-Heated,Buffered And Conventional 4 Percent Articaine In Mandibular Molars With Symptomatic Irreversible Pulpitis- A Randomized Double Blind Clinical Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089005

Enrollment

Registered

2025-06-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: pre-heated 4% Articaine: Heating the anesthetic may increase its lipid solubility and diffusion through nerve membranes, speeding up the blockade. Dose (ml)- 1.7 x Body weight(kg). rou

Eligibility

Inclusion criteria

Inclusion criteria: Pateint between the age group of 19-35 Pateints diagnosed with Symptomatic Irreversible pulpitis in mandible first or second molar Absence of any periapical radiolucency on radiographs are included

Exclusion criteria

Exclusion criteria: Patients with allergy to Local anaesthesia. Patients with known hypersensitivity to Articaine and Sodium bicarbonates. Pateints with systemic disease such as Diabetes mellitus, Hypertensive, Cardiovascular disorders, and patients who are under tranquilizers and sedatives. Pregnancy and lactating females. Patient with necrosed teeth with sinus or swelling , severe periodontitis.Patients who had taken analgesics within 24h preceding the commencement of the endodontic procedure are not included.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the anesthetic efficacy and injection pain using inferior alveolar nerve block with pre-heated, buffered and conventional 4%Articaine in patients with symptomatic irreversible pulpitis .Injecting pre-heated ,buffered local anesthetic solution can be a better alternative to conventional inferior alveolar nerve block.Timepoint: To evaluate and compare the anesthetic efficacy and injection pain using inferior alveolar nerve block with pre-heated, buffered and conventional 4%Articaine in patients with symptomatic irreversible pulpitis .Injecting pre-heated ,buffered local anesthetic solution can be a better alternative to conventional inferior alveolar nerve block.Injection pain will be assessed immediately after administration of the LA, Efficacy will be assessed intraoperatively.	—

Measure

Time frame

To evaluate and compare the anesthetic efficacy and injection pain using inferior alveolar nerve block with pre-heated, buffered and conventional 4%Articaine in patients with symptomatic irreversible pulpitis .Injecting pre-heated ,buffered local anesthetic solution can be a better alternative to conventional inferior alveolar nerve block.Timepoint: To evaluate and compare the anesthetic efficacy and injection pain using inferior alveolar nerve block with pre-heated, buffered and conventional 4%Articaine in patients with symptomatic irreversible pulpitis .Injecting pre-heated ,buffered local anesthetic solution can be a better alternative to conventional inferior alveolar nerve block.Injection pain will be assessed immediately after administration of the LA, Efficacy will be assessed intraoperatively.

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Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDrNPraveen

Karpaga Vinayaga Institute Of Dental Sciences

praveenendo@gmail.com9941277622

Outcome results