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Lazy eye study: Comparison of patching Vs home based ocular exercise

Assessment of Practices and Comparative Evaluation of Vision Therapy and Patching Therapy for Anisometropic Amblyopia in Eastern Nepal

Status
Unknown
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088970
Enrollment
70
Registered
2025-06-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H530- Amblyopia ex anopsia

Interventions

Intervention1: Home based vision therapy: 1) An additional pair of spectacles optimized for the best possible binocular vision will be provided to the patient (fogged normal eye to the visual acuity l

Sponsors

Mechi Drishti Eye Hospital Research Center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 5 to 20 years Diagnosis of unilateral anisometropic amblyopia (more than 2 lines difference in BCVA between eyes) Best corrected visual acuity (BCVA) in the amblyopic eye between 6/12 and 6/60 No prior amblyopia treatment or treatment discontinued at least 6 months ago Parents/guardians willing to provide informed consent

Exclusion criteria

Exclusion criteria: Presence of strabismus Bilateral amblyopia Ocular pathology (e.g., cataract, retinal disease) Neurological or developmental disorders affecting vision therapy compliance Inability to attend follow-up visits

Design outcomes

Primary

MeasureTime frame
Change in Best Corrected Visual Acuity (BCVA) in amblyopic eye (measured with LogMAR chart)Timepoint: 4 months after either of the intervention

Secondary

MeasureTime frame
Improvement in stereoacuity (Randot test or similar) Parental compliance with therapy (logbook review) Number of patients improved more than 3 line of visual acuity. Contrast sensitivity Timepoint: Baseline (Week 0) Week 4 (for optical saturation) Week 8 Week 12 Week 16

Countries

Nepal

Contacts

Public ContactAjit Kumar Thakur

Chitkara University

anita.gupta@chitkara.edu.in00919876054823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026