Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Three arm parallel study Group 1: Perineural dexmedetomidine 5 mcg plus Intravenous dexamethasone 8 mg
Intervention2: Three arm parallel study Group 2: Perineural dexamethasone 8 mg pl
Sponsors
Pravin K
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists ASA physical status I II or III who were scheduled for elective upper extremity surgery under supraclavicular BPB Both elective and emergency surgeries
Exclusion criteria
Exclusion criteria: Contraindication for BPB Refusal to consent severe coagulopathy sepsis infection at the block site Preexisting neuropathy of the surgical limb Pregnancy BMI more than 35 kg per m2 Patient on an alpha agonist as a hypertensive medication Uncontrolled Diabetes Mellitus RBS more than 250 mg per dl Actual body weight less than 40 kg
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Duration of analgesia time between block completion and the first request for analgesic supplementation Timepoint: Primary outcome: Duration of analgesia time between block completion and the first request for analgesic supplementation Secondary outcomes 1Includes motor block duration defined as the time between block completion and complete resolution of the motor block; a score of 2 in the 3-point modified Bromage score 2.The duration of sensory blockade is defined as the time between block completion (withdrawal of block needle) and resolution of sensory block (Temperature) at the dermatomal level of C5). 3.Sensory block onset (time between block completion and sensory block (Temperature) at the dermatomal level of C5). 4.Motor block onset (time between block completion and achieving score of 1 in 3-point modified Bromage Scale); | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes 1 Includes motor block duration defined as the time between block completion and complete resolution of the motor block; a score of 2 in the 3-point modified Bromage score 2. The duration of sensory blockade is defined as the time between block completion (withdrawal of block needle) and resolution of sensory block (Temperature) at the dermatomal level of C5). 3. Sensory block onset (time between block completion and sensory block (Temperature) at the dermatomal level of C5). 4. Motor block onset (time between block completion and achieving score of 1 in 3-point modified Bromage Scale); Timepoint: | — |
Countries
India
Contacts
Public ContactPravin K
AIIMS Guwahati
Outcome results
None listed