Health Condition 1: C227- Other specified carcinomas of liver
Conditions
Interventions
Intervention1: Immunomax powder: In addition to their usual intake, patients in the intervention arm will be prescribed for each of the 7 consecutive days preceding surgery 6-9 scoops
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with liver tumours planned for major hepatectomies (defined as resection of more than or equal to 3 liver segments) 2. ASA class I-III
Exclusion criteria
Exclusion criteria: 1. Preoperative severe renal failure (estimated glomerular filtration rate less than 30 ml permin) 2. History of hypersensitivity to arginine, omega-3 fatty acids, or nucleotide. 3. Inability to take oral nutrition 4. Pregnancy 5. Mental condition rendering the subject unable to understand the nature, endpoints and consequences of the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean difference in PNI points between intervention and control groupTimepoint: measurements will be repeated on the day prior to surgery (D-1) and on POD 1, 3, 5 and 7 and Post operative day 30 | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of 90 days mortalityTimepoint: till post operative 90 day;Incidence of postoperative complicationsTimepoint: Post operative day 1, 3, 5 and 7 and 30;Incidence of post-hepatectomies liver failure (PHLF)Timepoint: POD 1, 3, 5 and 7;Length of ICU stayTimepoint: till dischare from ICU or death;Length of hospital stayTimepoint: till discharge from hospital or death | — |
Countries
India
Contacts
Public ContactDr Shraddha Patkar
Tata Memorial Hospital, Mumbai
Outcome results
None listed