A clinical study to evaluate the effect of GLUMA and nano-hydroxyapatite in management of post vital tooth preparation hypersensitivity

Comparison of the effect of nano-hydroxyapatite and GLUMA in reducing post vital tooth preparation hypersensitivity: A Randomized controlled study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088907

Enrollment

Registered

2025-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K14- Diseases of oral cavity and salivary glands

Interventions

Intervention1: Nano-hydroxyapatite: Effect of nano-hydroxyapatite in reducing post vital tooth preparation hypersensitivity Control Intervention1: Nano-hydroxyapatite with GLUMA: Effect of nano-hydrox

Eligibility

Inclusion criteria

Inclusion criteria: Missing premolars and molars in maxilla and mandible Need for fixed dental prosthesis Absence of periodontal pathology or restorations ASA I and ASA II patients

Exclusion criteria

Exclusion criteria: Missing anterior teeth in maxilla and mandible ASA III and ASA IV and ASA V patients Active dental caries in abutment teeth Pregnant patients Non-vital teeth Allergic to desensitizers Patients smoking greater than 15 cigarettes per day Chronic alcoholics Amelogenesis or Dentinogenesis imperfecta Patients with orofacial pain

Design outcomes

Primary

Measure	Time frame
Comparison of the effect of nano-hydroxyapatite and GLUMA in reducing post vital tooth preparation hypersensitivity at baseline, two weeks and one monthTimepoint: 1 month	—

Secondary

Measure	Time frame
To evaluate and compare the effect of GLUMA in reducing dentinal hypersensitivity post vital tooth preparation at baseline, two weeks and one monthTimepoint: 1 month;To evaluate and compare the effect of nano-hydroxyapatite in reducing dentinal hypersensitivity post vital tooth preparation at baseline, two weeks and one monthTimepoint: 1 month	—

Countries

India

Contacts

Public ContactDr Varsha Revankar

Government Dental College and Hospital Hyderabad

drsreeramulub@gmail.com9052030499

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026