Efficacy of Sodium Hypochlorite, Chlorhexidine, Ozonated Olive Oil, and Diode Laser in Treating Irreversible Pulpitis

Comparative Evaluation of Antimicrobial Efficacy of 5.25 percentage Sodium hypochlorite, 2 percentage Chlorhexidine, Ozonated Olive Oil and Diode laser In Irreversible Pulpitis Cases - A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088883

Enrollment

Registered

2025-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: 5.25% Sodium hypochlorite, 2% Chlorhexidine, Ozonated Olive Oil and Diode laser: In the randomized controlled trial Comparative Evaluation of Antimicrobial Efficacy of 5.25% Sodium Hypo

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring endodontic treatment with irreversible pulpitis and single rooted teeth will be included in the trial

Exclusion criteria

Exclusion criteria: 1. Medically / systemically compromised patients 2. Teeth where full working length cannot be reached 3. Teeth with periapical radiolucencies 4. Traumatic injuries 5. Teeth with developmental anomalies 6. Patients who do not give informed consent

Design outcomes

Primary

Measure	Time frame
Reduction in microbial load by assessing the changes in bacterial colony forming unitsTimepoint: Baseline, post-operatively 12 hours, 24 hours	—

Secondary

Measure	Time frame
Antimicrobial efficacy achievedTimepoint: After 12 hours, 24 hours	—

Countries

India

Contacts

Public ContactDr Akash Shailesh Thakare

Sharad Pawar Dental College

doc.shwets@gmail.com9561468222

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026