A comparative study of dexmedetomidine and dexamethasone as adjuvants to 0.5 Percentage bupivacaine in ultra sound guided supraclavicular brachial plexus block for upper limb surgeries.

A Randomized comparative study to evaluate the analgesic effect of dexmedetomidine versus dexamethasone as an adjuvant to 0.5 percentage bupivacaine in ultra sound guided supraclavicular brachial plexus block in upper limb surgeries at SMS Hospital, Jaipur. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088850

Enrollment

Registered

2025-06-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: USG Guided Supraclavicular Block: USG Guided Supraclavicular Block using 20 ml of 0.5% Bupivacaine plus 50mcg(0.5ml) of Dexmedetomidine plus 1.5 ml ofnormal saline in patients of upper

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients posted for upper limb surgeries 2.patients who will give informed written consent 3.patients of either sex 4.Age 20 to 60 years 5.American Society of Anesthesiologists Physical Status Classes 1 and 2

Exclusion criteria

Exclusion criteria: 1.Patients with coagulopathies 2.Patients allergic to study drugs 3.Patients having peripheral neuropathy or motor neuron disorders 4.Patients with local site infection

Design outcomes

Primary

Measure	Time frame
Total duration of AnalgesiaTimepoint: At 0 min At 5 min At 10 min At 15 min At 20 min At 25 min At 30 min At 45 min At 60 min At 75 min At 90 min At 4 hours At 8 hours At 12 hours At 16 hours At 20 hours At 24 hours	—

Secondary

Measure	Time frame
1. Mean time of onset of sensory block 2. Mean time of onset and duration of motor block 3. Mean of hemodynamic parameters: (Mean Heart Rate, Mean Systolic Blood Pressure, Mean Diastolic Blood Pressure, Mean Blood Pressure,Mean Spo2) 4. Percentage of cases who develop adverse effectsTimepoint: onset of sensory and motor block At 2 min At 4 min At 6 min At 8 min At 10 min At 12 min At 14 min At 16 min At 18 min At 20 min At 22 min At 24 min At 26 min At 28 min At 30 min hemodynamic variables,mean duration of motor block,adverse effects At 5 min At 10 min At 15 min At 20 min At 25 min At 30 min At 45 min At 60 min At 75 min At 90 min At 4 hours At 8 hours At 12 hours At 16 hours At 20 hours At 24 hours	—

Measure

Time frame

1. Mean time of onset of sensory block 2. Mean time of onset and duration of motor block 3. Mean of hemodynamic parameters: (Mean Heart Rate, Mean Systolic Blood Pressure, Mean Diastolic Blood Pressure, Mean Blood Pressure,Mean Spo2) 4. Percentage of cases who develop adverse effectsTimepoint: onset of sensory and motor block At 2 min At 4 min At 6 min At 8 min At 10 min At 12 min At 14 min At 16 min At 18 min At 20 min At 22 min At 24 min At 26 min At 28 min At 30 min hemodynamic variables,mean duration of motor block,adverse effects At 5 min At 10 min At 15 min At 20 min At 25 min At 30 min At 45 min At 60 min At 75 min At 90 min At 4 hours At 8 hours At 12 hours At 16 hours At 20 hours At 24 hours

—

Countries

India

Contacts

Public ContactDr Suhani Shekhawat

SAWAI MAN SINGH MEDICAL COLLEGE

poonamkalra24@gmail.com9413416787

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026