FindTrial
Sign In

Study to determine effect of cisplatin causing acute and chronic kidney damage in head and neck and cervix cancer patients during radiation treatment

Assessment of severity and risk factors for nephrotoxicity in Head & Neck and Cervix carcinoma patients on cisplatin based chemoradiation - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088815
Enrollment
271
Registered
2025-06-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified Health Condition 2: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Dr Shubhada Agarwal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 years, histologically confirmed squamous/Adeno/adeno-squamous cell carcinoma of Head and Neck or Cervix region, planned for radical or adjuvant chemoradiation with concurrent cisplatin based weekly or 3 weekly chemotherapy

Exclusion criteria

Exclusion criteria: Prior renal irradiation Creatinine clearance less than 45 ml/min Patients who did not give consent for study

Design outcomes

Primary

MeasureTime frame
To assess the incidence and severity of nephrotoxicity in Head and Neck and Cervical carcinoma patients on concurrent cisplatin based chemoradiationTimepoint: 3 months—

Secondary

MeasureTime frame
To determine the risk factors for acute kidney injury (as per KDIGO Criteria) Timepoint: 3 months;To determine the risk factors for chronic kidney disease (as per KDIGO Criteria) Timepoint: 3 months;To explore the feasibility of developing risk prediction model based on above observations Timepoint: 3 months—

Countries

India

Contacts

Public ContactDr Pooja Sethi

JIPMER

docpujasethi@gmail.com9543601257

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026