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Comparing key periodontal pathogens in patients with cardiovascular disease

Comparative evaluation of the key periodontal pathogens among coronary heart disease and valvular heart disease in periodontitis subjects - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088803
Enrollment
20
Registered
2025-06-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I080- Rheumatic disorders of both mitraland aortic valves Health Condition 2: I708- Atherosclerosis of other arteries Health Condition 3: K053- Chronic periodontitis

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil Intervention7: Nil: Nil Intervention8: Nil: Nil Interven

Sponsors

Indian Council of Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Minimum of 10 natural teeth 2)In group 1, no gingival inflammation ( pocket depth less than or equal to 3 mm, clinical attachment loss (CAL) should be 0 mm) 3)In group 2,3 and 4, grade 3 and 4, that is individuals with inflammed gingival tissues with evidence of bleeding, local factors and pocket depth more than or equal to 5mm demonstrating CAL in 30 percentage or more of the teeth sites assessed to be included. 4)In case of group 3 and 4, patients with coronary heart disease and stenotic valves to be included.

Exclusion criteria

Exclusion criteria: 1)Patients who had undergone periodontal therapy within the previous 6 months. 2)Sarcoidosis patients. 3)Carcinoma patients. 4)Rheumatic arthritis patients. 5)Tuberculosis patients. 6)Immunosuppressive conditions. 7)Patients with other inflammatory diseases except diabetes mellitus.

Design outcomes

Primary

MeasureTime frame
To identify and compare the key periodontal pathogens in generalized chronic periodontitis patients associated with coronary artery disease and stenotic valve disease.Timepoint: baseline—

Secondary

MeasureTime frame
Impact of periodontal pathogens and their virulence factors on cardiac patientsTimepoint: Baseline—

Countries

India

Contacts

Public ContactDr Paavai Ilango

Priyadarshini Dental College & Hospital

drpaavaiilango@gmail.com9003091193

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026