Health Condition 1: K009- Disorder of tooth development, unspecified
Conditions
Interventions
Intervention1: The intervention in this study is a single oral dose of ibuprofen 400 mg administered one hour prior to the orthodontic extraction procedure. Ibuprofen is a non-steroidal anti-inflammat
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Healthy subjects aged 14 - 35 years (Both genders) ASA I classification, Require bilateral maxillary and mandibular premolar extractions for orthodontic treatment. Surgical sites should be comparable in terms of difficulty. Both premolars should be free of active infection, periodontal disease, or extensive decay, with adequate bone support and no signs of impaction or surgical complications at the extraction site. Participants (or guardians, if minors) must provide written informed consent. Patients without deleterious habits such as pan/gutka chewing, smoking, and alcohol use.
Exclusion criteria
Exclusion criteria: Recent (within 7 days) or concurrent use of anti-inflammatory drugs, corticosteroids, or other medications that may interfere with pain assessment. Allergy or hypersensitivity to the analgesic agents being studied, Active gastrointestinal bleeding or peptic ulcer. Significant differences in surgical difficulty between sides, the presence of impacted or supernumerary teeth in the extraction area. Patients with systemic illnesses such as diabetes, bleeding disorders. Women who are pregnant, planning to conceive. Patients with intellectual disability affecting pain perception or adherence to protocols, as well as those with extreme dental anxiety interfering with pain reporting.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate effectiveness of preemptive analgesia in reducing postoperative pain after orthodontic extractions using a 10-point visual analog scale.Timepoint: 1, 6, 12, 24, 48 hours post extraction | — |
Secondary
| Measure | Time frame |
|---|---|
| data will be collected for both groups regarding the use of rescue medication, including: (1) The time interval between the completion of the surgical procedure and the patient s first analgesic intake. (2) The total number of rescue analgesic doses consumed. Adverse events will also be recorded to assess the overall effectiveness and safety of the intervention.Timepoint: 1, 6, 12, 24, 48, and 72 hours after surgery | — |
Countries
India
Contacts
Public ContactFrijo Xavier
All India Institute of Medical Sciences (AIIMS) BIBINAGAR, HYDERABAD
Outcome results
None listed