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A study on comparing healing after root end microscopic surgery using a natural blood healing gel with or without light therapy

Investigating Periapical Healing Following Endodontic Microsurgery Using Autologous Grafts With or Without Photobiomodulation A Randomized Controlled Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088758
Enrollment
28
Registered
2025-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K046- Periapical abscess with sinus Health Condition 3: K047- Periapical abscess without sinus Health Condition 4: K048- Radicular cyst Health Condition 5: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Photobiomodulation: Photobiomodulation (808nm, 100 mW, and 4J/cm2 ) applications will be made in the immediate postoperative period and 24 hours after endodontic microsurgery and PRF pl

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients within 18 40 years of age who will give a written consent to participate in the study 2. Single rooted, maxillary anterior teeth. 3. Teeth with peri apical radiolucency indicated for surgery. 4. Patient should be of sufficient mental capacity and be in possession of all essential information. 5. Patients who are not on any medication affecting periapical healing. (corticosteroids, chemotherapeutic agents, non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, anticoagulants and drugs which reduce osteoblastic activity).

Exclusion criteria

Exclusion criteria: 1. Patients who did not give their consent for participating in the study. 2. Patients having insufficient motivation to report back for follow up visits. 3. Patients with any systemic diseases like diabetes mellitus, hypertension, hepatitis, Human immunodeficiency virus, bone disorders, auto-immune disorders. 4. Surgical retreatment cases. 5. Patients with malignant tumors or undergoing chemotherapy/radiotherapy. 6. Pregnant females. 7. Patients with periodontally compromised teeth.

Design outcomes

Primary

MeasureTime frame
Clinical Assessment of soft tissue healing and postoperative pain. Radiographic Assessment of healing.Timepoint: Clinical Assessment to be done at 24 hrs, 3 days and 7 days postoperatively Radiographic Assessment to be done at 1 month and every 3 month interval upto 1 year

Secondary

MeasureTime frame
Assessing soft tissue healing and increase in microvascualture using Ultrasonography with Color Doppler and 3D bone fill using CBCTTimepoint: Ultrasonography with Color Doppler to be done at 3,6, 9 and 12 months.CBCT Assessment to be done at 6 months and 1 year

Countries

India

Contacts

Public ContactDr Rakesh Kumar Yadav

King Georges Medical University

dr.vijay.shakya@gmail.com9140230667

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026