A COMPARATIVE STUDY OF PRE OXYGENATION BETWEEN PRESSURE SUPPORT WITH POSITIVE END EXPIRATORY PRESSURE, USING PRESSURE SUPPORT VENTILATION AND SPONTANEOUS BREATHUNG WITH FACE MASK DURING GENERAL ANAESTHESIA IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANAESTHESIA TO COMPARE SAFE APNEA TIME

A COMPARATIVE STUDY OF PRE OXYGENATION WITH PRESSURE SUPORT VENTILATION , PRESSURE SUPPORT VENTILATION WITH THE POSITIVE END-EXPIRATORY PRESSURE, AND SPONTANEOUS BREATHING WITH FACE MASK DURING GENERAL ANAESTHESIA - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088736

Enrollment

105

Registered

2025-06-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Preoxygenation with Pressure Support Ventilation: Preoxygenation with PSV (FiO2-1, face mask, PSV OF 10 CmH20 ) Intervention2: Preoxygenation with Pressure Support Ventilation and Posit

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to age group 18to 65 years undergoing elective operative procedure under general anesthesia. 2. ASA grade 1 and grade 2 3. Patients Room air peripheral oxygen saturation of more than 97% 4. Body mass index (BMI) of 18 to 26.0 kg per metre square

Exclusion criteria

Exclusion criteria: 1.Patients with history of respiratory disease 2.Patients having lesions / tumours of tracheobronchial tree and upper airway. 3.Patients with history of cardiac disorder affecting the effort tolerance 4.Patients with history of neurological disorder and neuromuscular disorders 5.Patients with anticipated difficult intubation. 6.Patients posted for emergency surgeries 7.Pregnant patients and patients with risk of aspiration

Design outcomes

Primary

Measure	Time frame
1. In all three groups time taken for desaturation till 92% of SpO2 (IN SECONDS) will be recorded . 2. Heamodynamic parameters (HR, NIBP) will be recordedTimepoint: AT BASELINE	—

Secondary

Measure	Time frame
Heamodynamic parameters (HR, NIBP) will be recordedTimepoint: MEASUREMENT ET EVERY MIUTE TILL SPO2 REACHES 92% AND AFTER 2 MINUTES OF VENTILATION LATER	—

Countries

India

Contacts

Public ContactDR RAMESH PRABHU

Srinivas Institute of Medical sciences and Research Centre

babcoelho@gmail.com9901243519

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026