Health Condition 1: R972- Elevated prostate specific antigen[PSA]
Conditions
Interventions
Intervention1: use of empirical antibiotics: The study group was advised to take antibiotic medication for 3 weeks. Preferred agents included fluroquilonones like Tablet. Levofloxacin 500 mg od. This
Sponsors
All India Institute of Medical Sciences Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: Male patients presenting with LUTS with elevated Serum PSA levels more than or equal to 4ng per ml
Exclusion criteria
Exclusion criteria: Documented prostate cancer or any other malignancy Documented metastatic disease Patients with hard nodule on DRE Patients with documented Urolithiasis. Patients with history of recurrent Urinary Tract Infection Patients with documented urethral stricture disease Patients with history of any prostate surgery in last 2 years Patients who do not consent to participate in study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether use of antibiotics in patients with elevated PSA leads to decrease in prostate biopsy ratesTimepoint: Baseline, 3 weeks and 5 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the decrease in serum PSA levels between patients receiving antibiotic therapy & those who do not. Assess the histopathological findings of prostate biopsies in patients with elevated PSA, correlating them with the use of antibiotics. To analyse mpMRI findings in study group & control group Timepoint: Baseline, 3 weeks & 5 weeks | — |
Countries
India
Contacts
Public ContactAmrut Phonde
All India Institute of Medical Sciences Bhopal
Outcome results
None listed