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Studying the Effectiveness of Probiotic Supplementation in patients with Allergic Rhinitis: A Randomized Controlled Trial

Investigating the Efficacy of Probiotic Supplementation in the Management of Allergic Rhinitis: A Randomized Controlled Trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088665
Enrollment
80
Registered
2025-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J309- Allergic rhinitis, unspecified

Interventions

Intervention1: Combination of Lactic acid bacillus, Nicotinamide, and Pyridoxine hydrochloride: Along with standard drugs probiotics will be administered orally once a day for 6 weeks Control Interve

Sponsors

Arupadai Veedu Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 upto 50 years attending ENT OPD in AVMC presenting with symptoms of allergic rhinitis with blood investigations supporting the diagnosis of allergic rhinitis.

Exclusion criteria

Exclusion criteria: Patients with a history of severe allergic reactions or other significant comorbidities. Patients currently using probiotics or undergoing immunomodulatory therapy. Pregnant or lactating women. Patients previously diagnosed with GERD

Design outcomes

Primary

MeasureTime frame
To asses Effectiveness of reducing symptoms and immunology marker levels .i.e. AEC count and Ige and diagnostic nasal endoscopy using probiotics as an adjunct with standard treatment for patients having Allergic Rhinitis.Timepoint: To asses Effectiveness of reducing symptoms and immunology marker levels at 2 weeks , 4 weeks ,6 weeks

Secondary

MeasureTime frame
To establish the association of Laryngeal reflux/Gastro- oesophageal reflux with allergic rhinitis.Timepoint: at 2 weeks , 4 weeks ,6 weeks

Countries

India

Contacts

Public ContactDr Sowmya Gajapathy

Aarupadai Veedu Medical College and Hospital

sowmya.rengaraj@avmc.edu.in8072351531

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026