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DEXMEDETOMIDINE and LIGNOCAINE In controlling blood pressure and heart rate during intubation

A Prospective, Randomized, Double-Blind Comparative Study of the Hemodynamic Response to Intravenous Dexmedetomidine Versus Lignocaine During Endotracheal Intubation - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088662
Enrollment
60
Registered
2025-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: A prospective study if intravenous lignocaine during endotracheal intubation: 30 patients lignocaine 1.5mg/kg in20 ml of 0.9% saline infusion over 3 minutes before induction Control Int

Sponsors

JLN medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I & II, age 18-55 yrs

Exclusion criteria

Exclusion criteria: Patients sensitive or allergic to drug,obese patient and with predicted difficult airway, and not willing to participate in study

Design outcomes

Primary

MeasureTime frame
To compare the haemodynamic changes during laryngoscope and endotracheal intubation with intravenous dexmedetomidine versus lignocaine from baselineTimepoint: To compare the haemodynamic changes during laryngoscope and endotracheal intubation with intravenous dexmedetomidine versus lignocaine from baseline—

Secondary

MeasureTime frame
Any adverse effect of dexmedetomidine & lignocaine such as hypotension, bradycardia, respiratory depression from baselineTimepoint: Any adverse effect of dexmedetomidine & lignocaine such as hypotension, bradycardia, respiratory depression from baseline—

Countries

India

Contacts

Public ContactDr Veena Mathur

JLNMC AJMER

veenamathur41@gmail.com9460517947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026