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A Study on Treatment Effects and Molecular Features in People with Signet Ring Cell Carcinoma of the Stomach.

A Study of Clinical Outcomes, Molecular Expression Analysis and In-Vitro Drug Response Analysis in Signet Ring Cell Carcinoma of the Stomach and the Gastroesophageal Junction. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088642
Enrollment
25
Registered
2025-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C169- Malignant neoplasm of stomach, unspecified

Interventions

Intervention1: Nil: Nil

Sponsors

Kasturba Medical College, Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with Gastric Signet Ring Cell Carcinoma and receiving standard therapy at the therapy. Patients who underwent surgery for Gastric Signet Ring Cell Carcinoma from 2019 to the present.

Exclusion criteria

Exclusion criteria: Patients diagnosed with Stage 4 Gastric Signet Ring Cell Carcinoma. Patients are not fit for Surgery or Chemotherapy. Patients receiving Neoadjuvant Therapy.

Design outcomes

Primary

MeasureTime frame
The expected outcomes of this study include a better understanding of why signet ring cell carcinoma is so aggressive, as well as the identification of key genes and pathways involved in tumor growth and drug resistance. The research aims to discover potential new targets for more effective and personalized treatments. By testing various drugs on these cancer cells in the lab, the study will provide insights into which therapies are most promising. Ultimately, these findings are expected to lead to improved treatment strategies and better outcomes for patients with this challenging type of cancer.Timepoint: Three years

Secondary

MeasureTime frame
Discovery of new biomarkers, such as specific proteins or genetic markers, that aid in early diagnosis or monitoring the effectiveness of treatments. The research might also provide a clearer understanding of why some patients develop resistance to chemotherapy over time, allowing for better management of treatment plans.Timepoint: Three years

Countries

India

Contacts

Public ContactDr Naveena Kumar A N

Manipal Academy of Higher Education

naveenkumar.an@manipal.edu9969523579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026