Can You Treat Knee Arthritis Without Surgery? Looking at Genicular Artery Embolization

Genicular Artery Embolization: Evaluating Its Efficacy as a Non-Surgical Treatment for Chronic Knee Pain in osteoarthritis. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088633

Enrollment

Registered

2025-06-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Genicular artery Embolization: Genicular Artery Embolization is a minimally invasive procedure where tiny PVA particles are injected into knee arteries to reduce blood flow, inflammatio

Eligibility

Inclusion criteria

Inclusion criteria: 1. Symptomatic patients aged 40 years and older diagnosed with Chronic OA knee based on clinical features and Knee radiographs. (Kellen- Lawrence Grade 1-3) 2. Failed medical management for OA knee. 3. Unwilling to Undergo TKA/ Not surgically fit for TKA.

Exclusion criteria

Exclusion criteria: 1. Kellen Lawrence Grade 4 on Knee radiograph 2. Active Knee infection 3. Underlying Inflammatory arthritis 4. Severe Peripheral Vascular disease (PVD) 5. Allergy to contrast media 6. Severe renal Impairment (eGFR less than 30 ml/min/1.73m2)

Design outcomes

Primary

Measure	Time frame
At least 25% improvement in the WOMAC and KOOS scores , post interventionTimepoint: 1 month, 3 months and 6 months post procedure	—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactYugandhar Samireddypalle

All India Institute of Medical Sciences - Mangalagiri

yugu.samireddypalle@gmail.com9930237652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026