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A Study of Salivary Defenses and Streptococcus mutans in Children with Early Childhood Caries

Assessment of Salivary Cathelicidin, Statherin and Streptococcus mutans in Early Childhood Caries: An Observational study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088619
Enrollment
40
Registered
2025-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil Intervention7: Nil: Nil

Sponsors

I.T.S Centre for Dental Studies and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Children aged lesser than 71 months of age. 2 Diagnosed with ECC (case group) and clinically caries-free (control group). 3 Healthy children without systemic illnesses or conditions affecting saliva production. 4 Children whose parents will give informed consent for participation in the study.

Exclusion criteria

Exclusion criteria: 1 Children using antibiotics and anti-inflammatory drugs for the last 2 months. 2 History of salivary gland disorders or systemic diseases affecting oral health. 3 Presence of oral ulcers, mucosal lesions, or dental trauma. 4 Inability to cooperate during saliva collection

Design outcomes

Primary

MeasureTime frame
Salivary Cathelicidin, Statherin, and Streptococcus mutans levels differ in children with ECC and without ECCTimepoint: The analysis of salivary cathelicidin, statherin, and Streptococcus mutans levels will be performed at this single time point using ELISA and culture—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Kalash Gupta

I.T.S Centre for Dental Studies and Research

shikhachoubey@hotmail.com9827248806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026