Health Condition 1: K040- Pulpitis
Conditions
Interventions
Intervention1: Nano-Tricalcium Silicate Cement group: After achieving hemostasis, Nano-Tricalcium Silicate Cement will be carefully placed as a 1 2 mm layer directly over the exposed and vital pulp t
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Patients must have at least two teeth, indicated for vital pulp therapy VPT due to caries or trauma, to facilitate the split-mouth design. The selected teeth must be suitable for VPT as per the American Association of Endodontists AAE guidelines. Patients must be between eighteen to forty five years of age, ensuring cooperation with the study protocol. Patients must provide informed consent and agree to attend all follow-up appointments as per the study timeline.
Exclusion criteria
Exclusion criteria: Patient who do not give written informed consent Teeth not indicated for VPT as per the guidelines of AAE. Patients with any systemic conditions or on any drugs e.g., diabetes that could affect healing or interfere with outcomes. Individuals with known allergies to medications used in the procedure. Patients unwilling or unable to comply with the follow-up schedule.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Focusing on parameters such as postoperative pain, sensitivity, and pulp vitality and particularly dentin bridge formation and evidence of successful pulp healing. Timepoint: Focusing on parameters such as postoperative pain, sensitivity, and pulp vitality and particularly dentin bridge formation and evidence of successful pulp healing. Clinical evaluations will be conducted at multiple intervals: 24 hours after the procedure to assess the immediate post-treatment response, 1, 3 and 6 months for further assessment of healing, and at 12, 24 and 36 months to evaluate the sustained clinical outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| Molecular biomarkers in pulpal and gingival crevicular fluid (GCF), including inflammatory and regenerative markers.Timepoint: 24 months | — |
Countries
India
Contacts
Public ContactDr Pragya Pandey
King George s Medical University, UP, Lucknow 226003
Outcome results
None listed