A Study to Compare Two Natural Healing Methods Injectable Platelet rich fibrin and Platelet rich fibrin membrane Used with Laser Treatment to Improve Dark Gums

Clinical evaluation of Injectable Platelet rich fibrin and Platelet rich fibrin membrane in Laser assisted gingival depigmentation. - A Randomized Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088594

Enrollment

Registered

2025-06-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K069- Disorder of gingiva and edentulousalveolar ridge, unspecified

Interventions

Intervention1: Injectable Platelet-Rich Fibrin: Injectable platelet-rich fibrin (i-PRF) contains high levels of growth factors, leukocytes, and platelets, resulting in a gradual and prolonged release

Eligibility

Inclusion criteria

Inclusion criteria: 1.Male and female with age range from 16 to 45 years old. 2.Systemically healthy patients. 3.Gingival hyperpigmentation on maxillary and mandibular labial keratinized gingiva score 3 (Dummett et al., 1964)

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women. 2.Gingival pigmentation associated with occupational hazards. 3.Patients with missing anterior teeth. 4.Patients with any metallic restoration related to anterior teeth or undergoing orthodontic treatment. 5.Smokers patients

Design outcomes

Primary

Measure	Time frame
Healing indexTimepoint: at 7th day	—

Secondary

Measure	Time frame
Dummett-Gupta Oral Pigmentation Index (DOPI)Timepoint: baseline, 1 week and 1 month;Gingival biotypeTimepoint: at baseline and after 1 month;Visual Analog Scale (VAS)Timepoint: at 3rd day and 7th day	—

Countries

India

Contacts

Public ContactRiddhika kochar

Km shah dental college , sumandeep vidyapeeth university Vadodra

drjasumaj@gmail.com9974005760

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026