THE EFFICACY OF NITROGLYCERIN LINGUAL SPRAY DIFFERENT DOSES 400MCG AND 800MCG IV LIGNOCAINE IN ATTENUATION OF PRESSOR RESPONSE FOLLOWING INTUBATION:A RANDOMISED CONTROLLED TRIAL

THE EFFICACY OF NITROGLYCERIN LINGUAL SPRAY 400MCG AND 800MCG IV LIGNOCAINE IN ATTENUATION OF PRESSOR RESPONSE FOLLOWING INTUBATION:A RANDOMISED CONTROLLED TRIAL. - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088589

Enrollment

Registered

2025-06-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: NITROGLYCERIN 400mcg lingual spray given Only once before 1 min doing laryngoscopy: comparing the different dose of nitroglycerin dosage 800 MCG and Requirement of nitroglycerin dose f

Eligibility

Inclusion criteria

Inclusion criteria: Group of patients comes under American society of Anaesthesia 1 and 2 undergoing surgery under General anaesthesia

Exclusion criteria

Exclusion criteria: Obstetrics patients Childrens Allergic to drug any type of Allegies Any patient refusal

Design outcomes

Primary

Measure	Time frame
Prevention of PRESSOR RESPONSE FOLLOWING INTUBATION using lingual spray of drugTimepoint: Prevention of PRESSOR RESPONSE FOLLOWING INTUBATION within minutes 1 min 2 min 5 min 10 min 15 min 20 min	—

Secondary

Measure	Time frame
Nil Reduction in the pressure response following intubation Might require higher doses aTimepoint: 1 minutes 3 minutes 5 minutes 10 Minutes 15 Minutes	—

Countries

India

Contacts

Public ContactDr Priyank V

BANGALORE MEDICAL COLLEGE AND RESEARCH INSTITUTE Bengaluru

priyabmc@yahoo.com9986539562

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026