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Assessing the Efficacy of Injectable Platelet Rich Fibrin Delivered Chlorhexidine in Treating Periodontal Pockets

Evaluation Of Injectable Platelet Rich Fibrin As a Novel Vehicle For Local Delivery Of Chlorhexidine In Periodontal Pocket: A Randomized Controlled Clinical Trial - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088587
Enrollment
88
Registered
2025-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Injectable Platelet Rich Fibrin: use of injectable platelet rich fibrin as a local drug delivery in four different groups comparing the efficacy of drug chlorhexidine along with injecta

Sponsors

Government Dental College Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: participants will be chosen on the basis of systemically healthy individual diagnosed with periodontitis stage II grade B with probing depth of more than 5 mm in at least two sites

Exclusion criteria

Exclusion criteria: Patients with hemogolobin level less than 11 mg/dL and having habit of smoking and pregnant women or patients under any antibiotic or anti inflammatory therapy

Design outcomes

Primary

MeasureTime frame
: Injectable platelet rich fibrin (iPRF) as a vehicle for delivery of chlorhexidine will cause effective release of drug in periodontal pocket with improvement in clinical and microbial parameters at follow up.Timepoint: 15 months

Secondary

MeasureTime frame
Injectable platelet rich fibrin (iPRF) based local chlorhexidine delivery will have better or comparable effectiveness when compared to commercially available chlorhexidine gel for delivery in periodontal pocket.Timepoint: 15 months

Countries

India

Contacts

Public ContactDr Alka Snehil

Government Dental College Raipur Chhattisgarh

agsangs@gmail.com7999308410

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026