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Comparative Assessment of Escitalopram, Venlafaxine and Fluoxetine on Psychomotor Performance in Patients with Major Depressive Disorder: A Parallel, Open Label, Prospective Observational Study

Comparative Assessment of Escitalopram, Venlafaxine and Fluoxetine on Psychomotor Performance in Patients with Major Depressive Disorder: A Parallel, Open Label, Prospective Observational Study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088544
Enrollment
57
Registered
2025-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F329- Major depressive disorder, singleepisode, unspecified

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Dr Avinash V Turankar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: HAM D score more than equal to 19 whoever willing to give informed consent form

Exclusion criteria

Exclusion criteria: Known patients of MDD on regular treatment. 2. Patient with any other long term treatment like antihypertensives, antidiabetics or antitubercular drugs and the drugs which interfere with psychomotor performance. 3. Patients with neurological disorders (dementia, stroke, seizures), cardiovascular diseases, serious or not stabilized organic disorder. 4. Patients who have h/o decreased visual acuity without correction & untreated angle closure glaucoma. 5. Pregnant and Lactating women. 6. Patients not willing to give written informed consent.

Design outcomes

Primary

MeasureTime frame
The difference in mean scores of critical flicker fusion frequencyTimepoint: Baseline, 4 weeks and 8 weeks

Secondary

MeasureTime frame
. The difference in mean scores of Hand Steadiness Test (HST), Reaction time monitoring, arithmetic ability test and Digit cancellation test from baseline to the end of 8 weeks. 2. The difference in mean scores of Hamilton Depression Rating Scale (HAM- D) from baseline to the end of 8 weeks.Timepoint: baseline to the end of 8 weeks.

Countries

India

Contacts

Public ContactDr Sivasakthi C

Government Medical College, Nagpur

aturankar@hotmail.com9822472329

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026