Comparative study of Maantha kudineer and Brahmi nei for the management Autism spectrum disorder

A Randomized comparative open-clinical trial of Siddha formulations Maantha kudineer and Brahmi Nei for the management of Maantha Sanni (Autism spectrum disorder) in children among out-patients attending Ayothidoss Pandithar Hospital, National Institute of Siddha. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088511

Enrollment

Registered

2025-06-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F840- Autistic disorder

Interventions

Intervention1: MAANTHA KUDINEER: Paediatric dose will be obtained by using Clarks rule The drug will be administered twice a day after food for 48 days. Control Intervention1: BRAHMI NEI: Paediatric d

Eligibility

Inclusion criteria

Inclusion criteria: Children with Indian Scale for Assessment of Autism (ISAA) scoring between 107 to 153(moderate Autism). Children who meets with the symptoms such as Poor eye contact Impaired social interactions Aggressive behaviour Engages in stereotyped repetitive behaviour Lack of communication skills

Exclusion criteria

Exclusion criteria: Attention deficit hyperactivity(ADHD) Cerebral palsy History of major mental illness (Bipolar affective disorder, Psychosis etc) Visual & hearing impairment Genetic syndromes Poor skull formation Patients receiving a psychotropic treatment

Design outcomes

Primary

Measure	Time frame
Effectiveness of trial drugs Maantha kudineer and Brahmi nei by comparing the impact on symptoms reduction in children using ISAA scale. Difference between the two arms in proportion of improvement from the symptoms using ISAA scale. Timepoint: 18 months	—

Secondary

Measure	Time frame
The characteristics of the trial drug Maantha Kudineer chooranam will be analysed as per PLIM guidelinesTimepoint: 18 months	—

Countries

India

Contacts

Public ContactDr K Vennila

National institute of Siddha

gvennils@gmail.com9789093986

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026