Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Oral Letrozole Group: Oral tablet letrozole was given 10 mg once daily dose for 3 days
Control Intervention1: Oral Mifepristone: Oral Mifepristone was given 200 mg single dose
Sponsors
Kajal Rani
Eligibility
Inclusion criteria
Inclusion criteria: 1. Females 18 years and above 2. Patient requesting for medical termination of pregnancy 3. Gestational age less than equal to twelve weeks on day one of a mifepristone or Letrozole administration) as confirmed by the first trimester dating scan.
Exclusion criteria
Exclusion criteria: 1. Haemoglobin levels less than 8 g/L. 2. Presence of intrauterine contraceptive device. 3. Breastfeeding females 4. Suspected ectopic pregnancy 5. Presence of abnormal uterine lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Letrozole is not inferior to Mifepristone for medical termination in the first trimester of pregnancy.Timepoint: Baseline, 3 days, 7 days, 14 days, 42 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects such as per vaginal bleeding were less common in patients administered letrozole compared to those who received mifepristone.Timepoint: DAy 3 , 7 | — |
Countries
India
Contacts
Public ContactHanslata Gehlot
Dr SNMC Jodhpur
Outcome results
None listed