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A study to compare efficacy of Oxytocin versus Carbetocin in high risk pregnancy

Comparison of Oxytocin and Carbetocin for prevention of post partum haemorrhage in high-risk pregnancy - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088477
Enrollment
340
Registered
2025-06-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O720- Third-stage hemorrhage

Interventions

Intervention1: Injection Carbetocin: Injection Carbetocin 100 microgram Intramuscular Stat, immediate after delivery(In Study group) Control Intervention1: Injection Oxytocin: Injection Oxytocin 10 In

Sponsors

PT JNM Medical college Raipur CG
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Grand multipara Hypertensive disorders in pregnancy Macrosomia Previous LSCS GDM Premature rupture of membrane Malpresentation Polyhydramnios Multiple gestation Prolonged and precipitate labour

Exclusion criteria

Exclusion criteria: Hypersensitivity to Oxytocin and Carbetocin Coagulation disorders Severe anemia Uterine pathology Placental retention

Design outcomes

Primary

MeasureTime frame
Assessment of maternal blood loss Modified shock index Difference in pre and post delivery hemoglobin Requirement of blood transfusion Duration of hospital stayTimepoint: Immediate after delivery at 30 minutes at 60 minutes and at 2 hour after delivery followed by 2 hourly till 24 hours

Secondary

MeasureTime frame
To observe any adverse effect of both drugs in Control group as well as in Study groupTimepoint: Immediate after drug administration followed by at 15 minute at 30 minute at 60 minute at 2 hour after drug administration

Countries

India

Contacts

Public ContactDR Garima Sahu

Pt J N M Medical college Raipur CG

dr.jyotijaiswal@gmail.com9893231900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026