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Comparing Dental Health and Saliva Composition in Children With Thalassemia and Those Without

Comparison Of Oral Health Status, Dental Caries Experience, Salivary Sialic Acid and Salivary Total Antioxidant Capacity in Thalassemic Children And Non Thalassemic Children. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088386
Enrollment
80
Registered
2025-06-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D758- Other specified diseases of bloodand blood-forming organs

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Rutika Gawand
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Non Thalassemic diagnosed children in age group of 5 to 12 years Children whose guardians are providing informed consent.

Exclusion criteria

Exclusion criteria: Presence of other systemic disease/s. Patient with cognitive impairment

Design outcomes

Primary

MeasureTime frame
The Thalassemic patients and their parents are preoccupied with their life-threatening problems arising from the disease and often neglecting the basic preventive dental care. This study would help the patients to take proper care of their oral hygiene as neglection of this may add to existing complications Relation between salivary biomarkers and oral health status in Thalassemic children will help us in preventive dental treatmentTimepoint: Thalassemic children and their parents often overlook oral health due to the burden of systemic illness. This study assesses the relationship between salivary biomarkers and oral health status to highlight the need for preventive dental care. The primary outcome correlation between salivary biomarkers and oral health indicators will be assessed at baseline, 4 weeks, and 8 weeks to guide early intervention strategies.

Secondary

MeasureTime frame
This study explores how thalassemia affects oral health & salivary composition. Primary outcomes (biomarker oral health correlation) will be assessed at baseline, 4 weeks, & 8 weeks. Secondary outcomes include changes in individual parameters over time, aiding in preventive care & screening in thalassemic children.Timepoint: This study explores how thalassemia affects oral health & salivary composition. Primary outcomes (biomarker oral health correlation) will be assessed at baseline, 4 weeks, & 8 weeks. Secondary outcomes include changes in individual parameters over time, aiding in preventive care & screening in thalassemic children.

Countries

India

Contacts

Public ContactRutika Gawand

Pravara Institute of Medical Sciences

opneeta23@gmail.com7972800076

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026