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Gelfoam with diclofenac placed after removing teeth compared with tablet diclofenac for relief of pain

Comparison Of Efficacy Of Gelfoam Soaked In Diclofenac Placed Inside Extraction Socket With Oral Diclofenac In Postoperative Analgesia. ?– A RANDOMISED SPLIT MOUTH STUDY - Nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088385
Enrollment
40
Registered
2025-06-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Local route for diclofenac post extraction: Diclofenac soaked gelfoam placed inside the extraction socket 50 mg diclofenac Placed for 7 days Control Intervention1: Oral route of diclofe

Sponsors

Dr Vini D Machchhar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with BILATERAL SYMMETRICAL MAXILLARY OR MANDIBULAR teeth indicated for extraction. 2.Patients undergoing intra-alveolar extraction within 10 minutes duration.

Exclusion criteria

Exclusion criteria: 1. Patients with known allergy to NSAIDS. 2. Pregnant women. 3. Patients on any other analgesics or corticosteroids. 4. Patients with history of systemic diseases like bronchial asthma, epilepsy, and emotional and psychosomatic disorders. 5. Patients unwilling to consent for the study.

Design outcomes

Primary

MeasureTime frame
The benefit is it helps determine the optimal route for diclofenac delivery based on factors like bioavailability and patient tolerance. Timepoint: Pain will be assessed for 7 days regularly and will be recorded Healing will be recorded at 7 days post extraction

Secondary

MeasureTime frame
The need for the current study is to examine and assess efficacy of diclofenac gel foam placed in extraction sockets as an alternative to oral analgesic. Timepoint: 6 months

Countries

India

Contacts

Public ContactVini D Machchhar

Yenepoya Dental College

jagadishmds@redfmail.com9845150871

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026