ALIGNER DISINFECTION USING UV CHAMBER, CHLORHEXIDINE GLUCONATE OR SALINE SOLUTION

COMPARISON OF EFFICACY BETWEEN UV CHAMBER AND CHLORHEXIDINE FOR DISINFECTION OF CLEAR ALIGNER MATERIAL:IN-VIVO STUDY - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088376

Enrollment

Registered

2025-06-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: UV chamber, Chlorhexidine Gluconate Solution: UV Chamber Disinfection: Clear thermoformed appliances are placed in a UV chamber and exposed to UV light for 30 minutes, according to the

Eligibility

Inclusion criteria

Inclusion criteria: Individuals with a sound dentition and full complement of teeth Class I occlusion with ideal or mild malocclusion Age group: 18-30 years

Exclusion criteria

Exclusion criteria: Individuals with skeletal malocclusion Individuals with missing teeth Individuals with prothesis Individuals with normal periodontal status

Design outcomes

Primary

Measure	Time frame
Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material.Timepoint: Base line-Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material. 1st day-Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material. 14th day- Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material.	—

Measure

Time frame

Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material.Timepoint: Base line-Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material. 1st day-Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material. 14th day- Effectiveness of UV chamber disinfection, chlorhexidine gluconate solution and saline solution for disinfection of clear aligner material.

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Secondary

Measure	Time frame
1. To evaluate the effectiveness of ultraviolet chamber disinfection 2. To evaluate the effectiveness of chlorhexidine gluconate solution. 3. To compare the effectiveness of UV chamber & chlorhexidine gluconate solution. 4. To determine whether physical or chemical disinfection is effective for aligner material.Timepoint: Baseline, 1st day & 14th day 1. To evaluate the effectiveness of ultraviolet chamber disinfection 2. To evaluate the effectiveness of chlorhexidine gluconate solution. 3. To compare the effectiveness of UV chamber & chlorhexidine gluconate solution. 4. To determine whether physical or chemical disinfection is effective for aligner material.	—

Measure

Time frame

1. To evaluate the effectiveness of ultraviolet chamber disinfection 2. To evaluate the effectiveness of chlorhexidine gluconate solution. 3. To compare the effectiveness of UV chamber & chlorhexidine gluconate solution. 4. To determine whether physical or chemical disinfection is effective for aligner material.Timepoint: Baseline, 1st day & 14th day 1. To evaluate the effectiveness of ultraviolet chamber disinfection 2. To evaluate the effectiveness of chlorhexidine gluconate solution. 3. To compare the effectiveness of UV chamber & chlorhexidine gluconate solution. 4. To determine whether physical or chemical disinfection is effective for aligner material.

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Countries

India

Contacts

Public ContactPuvvula Navya

sree sai dental college and research institute

pnavyakalyan@gmail.com8121821539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026