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Comparing the Germ-Fighting Power of Propolis, Calcium Hydroxide, and Antibiotic Paste in Treating Infected primary Teeth

Comparative evaluation of antimicrobial efficacy of Propolis, Calcium hydroxide and Double antibiotic paste as intracanal medicament in primary non vital teeth. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088312
Enrollment
45
Registered
2025-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Propolis: propolis powder mixed with saline into a paste form and placed as an intracanal medicament for one week Intervention2: Calcium Hydroxide: calcium Hydroxide powder mixed with p

Sponsors

DR.MOHD ABDUL GHANI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Non vital teeth. Two third of root should be present. Children with parental consent.

Exclusion criteria

Exclusion criteria: Teeth with less than two thirds of root. Pulpal involvement requiring pulp therapy but not involving the peri radicular tissues. Teeth with root caries. Children with systemic illness Periapical lesions with poor prognosis indicated for extraction Children without parental consent

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of Propolis, Calcium hydroxide and double antibiotic paste as intracanal medicaments.Timepoint: base line at one week

Secondary

MeasureTime frame
To evaluate the efficacy of propolis as an intracanal medicament To evaluate the efficacy of calcium hydroxide as an intracanal medicament To evaluate the efficacy of double antibiotic paste as an intracanal medicament Timepoint: the microbial culture will be checked after opening the access cavity & after one week baseline after one week

Countries

India

Contacts

Public ContactSilla Swarna Swathi

sri sai college of dental surgery

swathi.swarna18@gmail.com9790215500

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026