Health Condition 1: I350- Nonrheumatic aortic (valve) stenosis
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Rajeev Nair
Eligibility
Inclusion criteria
Inclusion criteria: Adults18 years scheduled for TAVR who are consenting to participate in the present observational study. Patients with severe symptomatic aortic stenosis Patients with other concomitant procedures (interventions for carotid disease, coronary interventions or other valve interventions) will be included Patients undergoing TAVR either under GA or CS or converted from sedation to GA
Exclusion criteria
Exclusion criteria: Patients with prior cerebrovascular accidents with significant neurological deficits Patients with incomplete cerebral oximetry data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the variations in cerebral oximetry by Near-Infrared Spectroscopy (NIRS) during TAVR.Timepoint: NIRS values baseline and various stages of procedure including during Ballon valvuloplasty, valve deployment, post deployment of valve. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the demographic characteristics & preoperative clinical profile of patients undergoing TAVR, including risk assessment using EUROSCORE-II, STS score, & FRAIL score. To analyze procedural details, including the type of valve implanted, procedure duration, & associated complications. To assess the influence of anaesthesia type (GA vs. CS) on cerebral desaturation & hemodynamic stability. To determine post-procedure outcomes, including mechanical ventilation duration, ICU stay, hospital readmission, & six-month mortality.Timepoint: One Month & six months | — |
Countries
India
Contacts
Public ContactV Hanumantha Rao
Army Hospital Research and Referral
Outcome results
None listed