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Comparsion of Non Buffered and Buffered Local Anesthesia in Inferior Alevolar Nerve Oral Submucous Fibrosis Patient

EFFECTIVENESS OF NON BUFFERED AND BUFFERED LOCAL ANESTHESIA IN INFERIOR ALVEOLAR NERVE BLOCK IN ORAL SUBMUCOUS FIBROSIS PATIENT: RANDOMIZED CONTROL TRIAL - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088299
Enrollment
160
Registered
2025-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K027- Dental root caries Health Condition 2: K029- Dental caries, unspecified Health Condition 3: K135- Oral submucous fibrosis Health Condition 4: K04- Diseases of pulp and periapical tissues Health Condition 5: K05- Gingivitis and periodontal diseases Health Condition 6: K03- Other diseases of hard tissues ofteeth

Interventions

Intervention1: local anestheisa containing 2 percent LIGNOCAINE WITH ADRENALINE IN RATIO 1:100000 BUFFERED WITH 8.4 PERCENT SODIUM BICARBONATE: 2 percent LIGNOCAINE WITH ADRENALINE IN RATION 1:100000

Sponsors

Government Dental College And Hospital Jamnagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Give written, informed consent. 2. Be 21-65 years of age 3. Patient should have Oral Submucous Fibrosis 4. mouth opening 25mm-30mm 5. Be able to comprehend the visual analog scale (instructions given to ascertain this). 6. Extraction of mandibular 1st molar,2nd molar

Exclusion criteria

Exclusion criteria: 1 Patient under 20 years and above 65 years 2 Pregnant women. 3 Patients with uncontrolled systemic diseases that are contraindicated for dental extraction. 4 Patient taking medication that interferes with the assessment of local anesthetic such as narcotics and antidepressants . 5 Patient with cardiac disease. 6 Patient cannot adhere to the schedule or is unwilling to give written consent.

Design outcomes

Primary

MeasureTime frame
Pain on injection by using numerical rating scale of 0 to 10 with 0 being painless and 10 maximum painTimepoint: Pain on injection will be assessed immediately after injection—

Secondary

MeasureTime frame
Onset time by subjective testing (seconds)Timepoint: First patient will be asked about the numbness & tingling sensation on the side of injection & than williams probe on buccal side of 1st premolar & asked about the loss of pain i.e our objective symtoms every 30 secs till the syymtoms appear;Onset time by objective testing (seconds)Timepoint:—

Countries

India

Contacts

Public ContactYash Ajmera

Governemt dental college and hospital

dr.rrandhawa23@gmail.com97973811010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026