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Study of skin microbiome in Patients with Atopic Eczema using advanced DNA sequencing

Comprehensive analysis of skin microbiome using Next generation sequencing in atopic dermatitis patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/088291
Enrollment
30
Registered
2025-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L20- Atopic dermatitis

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Research department Amrita Institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.All patients, above 12 years with and without prior treatment. Informed consent from adult patients as well as parents of the children who will be enrolled in the study shall be sought. 2.Subject under study are individuals with clinically diagnosed atopic dermatitis by two independent dermatologists. 3.Patients with atopic eczema thatfulfil the diagnostic criteria of Hanifin-Rajka.

Exclusion criteria

Exclusion criteria: 1. Patients who had severe chronic diseases (liver and kidney diseases, malignancy, diabetes, growth failure, obesity, primary immune deficiency, etc.) 2.Patients who had topical medical treatments (steroids and antibiotics), systemic antibiotics. 3. Patients who had showered in the past 12-24 hours.

Design outcomes

Primary

MeasureTime frame
To compare the diversity of skin microbiome communities between diseased and non-diseased skinin atopic dermatitis patients Timepoint: at baseline

Secondary

MeasureTime frame
To correlate the skin microbiome diversity with disease severity using SCORAD To correlate the skin microbiome diversity with relevant lab investigations - eosinophil counts & IgE levels Timepoint: at baseline

Countries

India

Contacts

Public ContactNamrata Pambavasan

Amrita Institute of medical sciences and research

drgopikrishnana@gmail.com7736811168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026