To compare postoperative analgesic efficacy after infiltrating Bupivacaine with Dexmedetomidine vs Bupivacaine alone at surgical incision site in below umbilical surgeries.

A Comparative study of postoperative analgesic efficacy after infiltrating Bupivacaine with Dexmedetomidine vs Bupivacaine alone at surgical incision site in below umbilical surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/088250

Enrollment

148

Registered

2025-06-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: K35-K38- Diseases of appendix Health Condition 3: K40-K46- Hernia Health Condition 4: K60- Fissure and fistula of anal and rectal regions Health Condition 5: K61- Abscess of anal and rectal regions Health Condition 6: M849- Disorder of continuity of bone, unspecified Health Condition 7: N20-N23- Urolithiasis Health Condition 8: N40- Benign prostatic hyperplasia Health Condition 9: N43- Hydrocele and spermatocele Health Condition 10:

Interventions

Intervention1: Bupivacaine: The study population is divided into 2 groups of 74 patients receiving 20mL 0.25% bupivacaine with normal saline 0.5ml for surgical incision Control Intervention1: Bupivac

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients giving informed consent to participate in the study. 2.All patients posted for below umbilicus surgeries. 3.Age of the patient between 18-50 years. 4.Patients belonging to ASA I & ASA II

Exclusion criteria

Exclusion criteria: 1.Patients with morbid obesity 2.Patients with Raynaud s disease 3.Patients belonging to ASA class III and IV. 4.Patients with co morbidities 5.Patients with infection at the site of infiltration. 6.Patients with psychiatric disorders. 7.Patients with history of hypersensitivity to any of the drugs under study.

Design outcomes

Primary

Measure	Time frame
To estimate the duration of postoperative analgesia after local infiltration in both groups, Bupivacaine alone and Bupivacaine mixed with DexmedetomidineTimepoint: at 5 minutes, 30 minutes, 45 minutes, 75 minutes, 90 minutes, 2hour, 4 hour, 6 hour, 12 hour, 24 hour	—

Secondary

Measure	Time frame
To calculate the total amount of rescue analgesic consumed in 24 hoursTimepoint: at 3 hour, 6 hour, 12 hour, 24 hour;To observe VAS score after infiltrationTimepoint: at 5 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes, 90 minutes, 2 hour, 4 hour, 6 hour, 12 hour, 24 hour;To observe the hemodynamic changes after local infiltration of Dexmedetomidine added to Bupivacaine at incision siteTimepoint: at 15 minutes, 30 minutes, 45 minutes, 60 minutes, 3 hour, 6 hour, 9 hour, 12 hour, 16 hour, 20 hour, 24 hour	—

Measure

Time frame

To calculate the total amount of rescue analgesic consumed in 24 hoursTimepoint: at 3 hour, 6 hour, 12 hour, 24 hour;To observe VAS score after infiltrationTimepoint: at 5 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes, 90 minutes, 2 hour, 4 hour, 6 hour, 12 hour, 24 hour;To observe the hemodynamic changes after local infiltration of Dexmedetomidine added to Bupivacaine at incision siteTimepoint: at 15 minutes, 30 minutes, 45 minutes, 60 minutes, 3 hour, 6 hour, 9 hour, 12 hour, 16 hour, 20 hour, 24 hour

—

Countries

India

Contacts

Public ContactDR AJAY KUMAR SINHA

Government Medical College And Sth, Haldwani

drajayksinha@yahoo.co.in9897672301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026