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Evaluating Remifentanil and Dexmedetomidine for Reducing Agitation and Improving Recovery in Children Undergoing Urogenital Surgeries

Comparative Evaluation of Remifentanil and Dexmedetomidine in Emergence Delirium and Recovery Profile in Pediatric subset Undergoing Urogenital Surgeries. - DREAM-P

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/088233
Enrollment
110
Registered
2025-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: Z768- Persons encountering health services in other specified circumstances

Interventions

Intervention1: Group Remifentanil: 1.0 mcg/kg of remifentanil diluted with 5cc saline will be administered 1 minutes before induction. 0.05 to 0.1 mcg/kg/min of remifentanil (flow rate comparable to 0

Sponsors

Dr Ridhima Sharma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The following patients will be included- patients aged 2 to 8 years, elective surgeries under general anesthesia at AIIMS Nagpur, duration of surgery more than 1 hour, ASA grade I or II

Exclusion criteria

Exclusion criteria: Patientss ages less than 2years and more than 8 years Emergencies surgeries Patiets parents or legal guardian not willing to participate Patients with developmental delay or pre-existing neurological disorders Patient with cardiac disorders History of allergy or medications being used

Design outcomes

Primary

MeasureTime frame
To assess and compare the incidence of emergence delirium between remifentanil versus Dexmedetomidine in paediatric patients undergoing urogenital surgeries.Timepoint: 1 month

Secondary

MeasureTime frame
1. To Compare perioperative Haemodynamics (Heart rate, Blood Pressure,) among two groups. 2. To Assess and Compare Recovery profile using Aldrete score between two groups. 3. To compare Satisfaction of parents between two groups 4. Incidence of PONV Timepoint: 1 month

Countries

India

Contacts

Public ContactDr Ridhima Sharma

AIIMS Nagpur

drridhimasharma@yahoo.com805459458

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026